I have nearly twenty years of experience as a synthetic biologist, movement builder, educator, designer, and artist. In that time, I have explored three theories of change that are each foundational to my work: first, a technical theory of change: what are transformative tools and technologies that can help change the world? As a synthetic biologist, I have pioneered the development of “lab-on-a-chip” devices for gene synthesis and genetic circuit assembly, organ-on-a-chip technologies (including artificial guts for prototyping microbial communities and artificial noses for augmented olfactory sensing), and am currently working on establishing a global cloud laboratory of liquid-handling robots to enable radically accessible learning and creativity in the life sciences. Second, a social theory of change: how can we empower communities and build movements that confer agency and power? For nearly fifteen years I served as founder and director of EMW Community Space, a community center in Cambridge, MA that served thousands of community members from marginalized backgrounds through art and technology programming. I am the founder of the Global Community Bio Summit, the annual movement event that brings together the global network of grassroots, community-led biology labs. Over the years we have worked with thousands of participants from more than 100 countries to co-design statements of shared purpose, codes of ethics, and governance frameworks. I am also co-inventor of the ‘Supermind Design’ methodology, a collective intelligence framework for designing more effective communities and other organizations. Third, a relational theory of change: how can we shift our underlying values and worldviews from extractive, utilitarian approaches to ones of mutualism and reciprocity, particularly with nature? I teach the MIT graduate course "Ancient Future Technology," where we explore how cutting-edge technologies like AI and synthetic biology can actualize worldviews where the natural world is our family and ancestors, instead of resources to be exploited. I am also working on a ‘Living Artifacts’ project, where we are developing novel biomaterials like bacterial bio cements to fabricate artifacts that we hope will impact our relationship with the materials of our environment. I have been integrating each of these three theories of change into a new design framework I have been developing called ‘Biotic Design,’ which explores the technical, social, and relational dimensions of designing with the living world. A major ‘Biotic Design’ project I am working on now involves eco-augmentation and deploying both technical and social innovations for coral conservation applications (e.g. coral probiotics for enabling temperature and disease resilience), with a current case study in Mo’orea. I am also helping to lead the visioning and establishment of a global ‘ECO-ARPA,’ which aims to develop novel eco-augmentation technologies that could help address some of our pressing ecosystem challenges. I would love to discuss any and all of these projects with colleagues on Earth One and explore how to collaborate, synergize, and amplify our collective work! Finally, I also love DJing (especially for nerds), and have performed as a DJ, beat-boxer, vocalist, and rapper at hundreds of venues, and teamed up with hip hop icon DJ Jazzy Jeff to make ‘Biota Beats’ from the human microbiome. My research and photography has also been exhibited at the National Museum of American History at the Smithsonian and in other museums and galleries around the world.